Our research is gaining a fundamental understanding of stem cells and regeneration and to use this to develop new models, diagnostics and therapies to improve human health. The centre hosts 26 research groups focus on four main research themes: Stem cell biology Tissue homeostasis and repair Reprogramming Translational and clinical programmes Our research aims to develop new treatments for major diseases, including: brain cancer, leukaemia, liver cirrhosis, multiple sclerosis and Parkinson’s disease. Diseases we study Pierre Bagnaninchi Research Group Cell and tissue monitoring Brian Bigger Research Group Developing stem cell gene therapies for childhood dementias and multisystem diseases Clare Blackburn Research Group Thymus generation and regeneration Guillaume Blin Research Group Quantitative Biology of Pattern Formation Ian Chambers Research Group Embryonic stem cell biology Stefano Comazzetto Research Group Metabolic regulation of normal and clonal haematopoiesis Mihaela Crisan Research Group Blood vessel stem cell biology Elaine Emmerson Research Group Manipulating the stem cell niche to promote regeneration Antonella Fidanza Research Group In vitro human hematopoiesis Stuart Forbes Research Group Liver stem cells and regeneration Dave Hay Research Group Liver Tissue Development and Engineering Robert Illingworth Research Group Epigenetics and Brain Development Keisuke Kaji Research Group Biology of reprogramming Tilo Kunath Research Group Mechanisms of neurodegeneration Sally Lowell Research Group Pluripotent stem cell differentiation Alexander Medvinsky Research Group Ontogeny of haematopoietic stem cells Dónal O'Carroll Research Group RNA function in germ and stem cell biology Katrin Ottersbach Research Group Developmental origins of blood stem cells and leukaemia Steve Pollard Research Group Neural stem cells and brain cancer Anura Rambukkana Research Group Adult tissue cell plasticity, reprogramming and regeneration Aida Rodrigo Albors Research Group Spinal cord regeneration across species Linus Schumacher Research Group Computational biology of cell populations Andrew Smith Research Group Stem cell genome engineering Abdenour Soufi Research Group Chromatin structure and cellular identity Simon Tomlinson Research Group Stem cell bioinformatics Anna Williams Research Group Remyelination in multiple sclerosis Val Wilson Research Group Early embryo development This article was published on 2024-02-26